A STUDY OF MICRONEEDLES FOR TRANSDERMAL DRUG DELIVERY SYSTEM
Mr.Anil Adhikari
, Mrs. Kanchan Tariyal , Mr.Salman Ahmad , Mr. Ayush Verma
Microneedles, transdermal drug delivery , polymer
Microneedles are based on microdevices to expands the scope for therapeutics agents and delivery of vaccines through skin and withdrawing bio-fluids for symptomatics. Microneedles are manufacturing from different materials like stainless steel, metals and polymers. These microneedles are used to deliver bioactive agents systematically and deliver insulin to the skin, with the potential to improve patient compliance and reduce pain associated with traditional needle injections. In terms of biocompatibility, the materials used to make microneedles are typically biodegradable and biocompatible, meaning that they do not cause any significant adverse reactions when introduced into the body. Some of the most commonly used materials for microneedles include silicon, metals, and biodegradable polymers. Research should be focused on genetic, antidiabetic, antiviral, oncological, dermatological, anti-osteoporosis, vaccine, etc., areas for improvement of bioavailability by developing microneedle-based transdermal drug delivery systems. Skins permeability are increased in different approaches of studied. Microneedles are fabricated employing microelectromechanical systems (MEMS). The safety of microneedles has been extensively studied are increasing in recent years. The numerous study are shows that these devices are generally safe and well-tolerated by patients. The two photon polymerization and 3D printing fabrication are promising transformative technologies are develope in recent years. In this articles provide an overview of microneedles systems application, manufacturing methods, types, drug delivery, designs, merits, demerits and application of microneedles.
"A STUDY OF MICRONEEDLES FOR TRANSDERMAL DRUG DELIVERY SYSTEM", IJCSPUB - INTERNATIONAL JOURNAL OF CURRENT SCIENCE (www.IJCSPUB.org), ISSN:2250-1770, Vol.13, Issue 2, page no.461-473, June 2023, Available :https://rjpn.org/IJCSPUB/papers/IJCSP23B1409.pdf
Volume 13
Issue 2,
June-2023
Pages : 461-473
Paper Reg. ID: IJCSPUB_216696
Published Paper Id: IJCSP23B1409
Downloads: 000119
Research Area: Pharmacy All
Country: Dehradun , Uttrakhand , India
ISSN: 2250-1770 | IMPACT FACTOR: 8.17 Calculated By Google Scholar | ESTD YEAR: 2011
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.17 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: RJPN (IJPublication) Janvi Wave
