SEVERE CIGARETTE SMOKING CAUSED PROSTATE CANCER AND BONY METASTASIS - A CASE STUDY
Dr. Humera Ayesha
, Syed Abbas Mujtaba
Severe Cigarette Smoking, Polycyclic Aromatic Hydrocarbons, Prostate cancer, PTEN mutation, Bony metastasis
Severe cigarette smoking is considered to be one of the largest addictions and has been a major health problem. Around 8 million people die due to smoking9. Estimated that 1 in 4 adult men in the world smoke tobacco which has carcinogenic agents like Polycyclic aromatic hydrocarbons (PAH)3 causing gene mutations4 such as PTEN5, PREX2, AGO2 which weakens immune system, DNA damage finally resulting in cellular proliferation and developing cancer. Along the side of lung cancer in smokers we observed that prostate11 cancer is also being diagnosed in the worldwide population among men, early deaths occurred due to bony metastasis2 for not quitting smoking. The associated gene mutation between smoking and prostate cancer can be PTEN through AKT activation pathway. severe cigarette smoking also contributes to heart disease and various other cancers like throat and gastric etc.
"SEVERE CIGARETTE SMOKING CAUSED PROSTATE CANCER AND BONY METASTASIS - A CASE STUDY", IJCSPUB - INTERNATIONAL JOURNAL OF CURRENT SCIENCE (www.IJCSPUB.org), ISSN:2250-1770, Vol.14, Issue 2, page no.223-226, May-2024, Available :https://rjpn.org/IJCSPUB/papers/IJCSP24B1253.pdf
Volume 14
Issue 2,
May-2024
Pages : 223-226
Paper Reg. ID: IJCSPUB_300923
Published Paper Id: IJCSP24B1253
Downloads: 000102
Research Area: Science and Technology
Country: Hyderabad , Telangana, India
ISSN: 2250-1770 | IMPACT FACTOR: 8.17 Calculated By Google Scholar | ESTD YEAR: 2011
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.17 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: RJPN (IJPublication) Janvi Wave