Published Thesis

Thesis Title: Comprehensive Management of COPD with Coexisting Conditions: Current and Emerging Treatment Strategies

  Published Thesis ID: - IJNTITH00002

  Registration ID - 230921

 Pages: 53-88

 Year: January-2025

  Author Name(s): Khushboo muzaffar, Sadaf nisar, Tawqeer shafi, S.k.Nayak

  Publisher Name: RJPN (IJPublication) Janvi Wave

Abstract

Chronic obstructive pulmonary disease (COPD) is one of the fastest-growing causes of deaths worldwide. Extrapulmonary dysfunction overlapping has a significant impact on the prognosis of COPD patients. Tobacco smoking and air pollutant are the major factors involved in the initial step of COPD development along with cardiopulmonary illness and lung cancer. Some multiple medical conditions, such as cardiac disease and nutritional deficiencies, are directly caused by chronic pulmonary disease. Additionally, venous thromboembolism, depressive disorders, insomnia, osteoarthritis, obesity, insulin resistance, iron deficiency etc. also associated comorbidities with COPD. Many of these extrapulmonary symptoms are triggered by a chronic inflammatory process that raises COPD cases, hospitalizations, and healthcare expenses as well as contributing to mortality independent of respiratory failure. Addressing these comorbidities is necessary for effective care of COPD, since these conditions generally complicate the treatment. Concurrent illnesses comprise cardiovascular disease, diabetes mellitus, hypertension, bone disease, and mental health difficulties, and their recurrent changes complicate the diagnosis of COPD and these disorders. Recent epidemiologic studies have demonstrated the harmful impact of these comorbidities on COPD patients. Understanding the relationship between COPD and its comorbidities, influenced by shared risk factors and chronic systemic inflammation, are crucial for developing effective therapeutic strategies. Emerging therapies targeting both COPD and its comorbidities, such as statins, phosphodiesterase 4 inhibitors, and antioxidants, have shown promising therapeutic options but require further research to optimize efficacy and minimize side effects.

Licence

Creative Commons Attribution 4.0 and The Open Definition

Keywords

COPD, comorbidites, chronic systemic inflammation, phosphodiesterase 4 inhibitors, chronic pulmonary disease, osteoarthritis

License

Creative Commons Attribution 4.0 and The Open Definition


Thesis Title: Karnataka Land Reform Act: Boon or Bane to the Farmers?

  Published Thesis ID: - IJNTITH00001

  Registration ID - 230705

 Pages: 1-52

 Year: November-2024

  Author Name(s): Harish N, Prof. Dr. Chandrakanthi L.

  Publisher Name: RJPN (IJPublication) Janvi Wave

Abstract

The Karnataka Land Reform Act, enacted in 1961, aimed to address historical inequities in land ownership and promote agrarian reform in the state. This legislation sought to limit landholdings, redistribute surplus land, and empower marginalised communities, thereby fostering social justice and economic development. This paper examines the dual aspects of the Act, evaluating whether it serves as a boon or bane for the agricultural landscape of Karnataka. Through a comprehensive analysis of its impact on land ownership patterns, agricultural productivity, and socio-economic conditions of rural populations, the study reveals that while the Act has facilitated significant advancements in land access for marginalised groups, challenges such as bureaucratic inefficiencies, land disputes, and resistance from traditional landowners have hindered its full potential. The findings suggest that the Act's success hinges on ongoing reforms, effective implementation, and stakeholder engagement, indicating that its role as a boon or bane is contingent upon evolving socio-political dynamics and administrative frameworks in Karnataka's agricultural sector.

Licence

Creative Commons Attribution 4.0 and The Open Definition