FORMULATION AND EVALUATION OF FAST DISSOLVING FILMS OF ZOLMITRIPTAN BY USING NATURAL POLYMER”
Mr. PANKAJ DEEPAK BHONDE
, Dr. Nikhil N. Jadhav
Migraine, ZOLMITRIPTAN, dissolving tablet, neurological.
Migraine is a neurological disorder characterized by recurrent episodes of severe headache, often accompanied by nausea, vomiting, photophobia, and phonophobia. It affects nearly 12–15% of the global population, with a higher prevalence in women compared to men. The World Health Organization (WHO) has listed migraine as one of the leading causes of disability worldwide, particularly in young and middle-aged adults (Steiner et al., 2018). Despite its prevalence, effective management of migraine remains a challenge due to variability in individual response, slow onset of action of conventional dosage forms, and gastrointestinal disturbances that impair oral drug absorption.
Zolmitriptan, a selective serotonin 5-HT1B/1D receptor agonist, is one of the most effective drugs used in the acute treatment of migraine. However, the conventional oral tablets of zolmitriptan suffer from limitations such as low oral bioavailability (40–45%), due to extensive first-pass metabolism and delayed onset of action. In conditions such as migraine, where rapid relief is essential, there is
"FORMULATION AND EVALUATION OF FAST DISSOLVING FILMS OF ZOLMITRIPTAN BY USING NATURAL POLYMER”", JETNR - JOURNAL OF EMERGING TRENDS AND NOVEL RESEARCH (www.JETNR.org), ISSN:2984-9276, Vol.4, Issue 3, page no.630-665, March-2026, Available :https://rjpn.org/JETNR/papers/JETNRTH00013.pdf
Volume 4
Issue 3,
March-2026
Pages : 630-665
Paper Reg. ID: JETNR_233437
Published Paper Id: JETNRTH00013
Downloads: 00084
Research Area: Pharmacy All
Country: AHILYANAGAR , Maharastra , India
ISSN: 2984-9276 | IMPACT FACTOR: 9.87 Calculated By Google Scholar | ESTD YEAR: 2023
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.87 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: RJPN (IJPublication) Janvi Wave
